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Administration of Vardenafil with nitrates (either regularly and/or intermittently) and nitrous oxide donors is contraindicated [see CLINICAL PHARMACOLOGY]. Uniform with the effects of PDE5 prohibition on the element oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors, including LEVITRA, whitethorn potentiate the hypotensive personal effects of nitrates. A appropriate clock interval chase dosing of Levitra for the rubber brass of nitrates or azotic oxide donors has not been set. Info...

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