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We analyze the interactions betwixt environmental exposure, catgut microbiota and Host exemption to translate fit intestine microbiota homeostasis and man physiopathology. We train to trace the use of adaptative resistance on intestine microbiota homeostasis, with specific stress on microbiota-particular immune serum globulin A (immuno-microbiota). The Cimi has a fluorescence microscopy platform for the imagery of keep cells, in exceptional for the work of host-pathogen interactions, or of flat stuff. A Zeiss Axio Observer microscope installed in a strong L2 surroundings allows the reflexion of livelihood cells, especially in the context of contagion. This will fix an immune signature tune encountered in ripening that May help oneself clinicians to delimitate vulnerable patients. Period cytometry is unmatchable of the activities at the nitty-gritty of many inquiry projects carried away at the Cimi. 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