Clinicians should discuss the cessation of testosterone therapy three to six months after commencement of treatment in patients who experience normalization of total testosterone levels but fail to achieve symptom or sign improvement. Chromium, for example, is a testicular toxicant thatstimulates lipid peroxidation and suppresses antioxidant enzyme activities as well as ascorbatelevels in the testes.113 Additional studies in monkeys have also shown that chromium administrationdecreases not onl...